From 1905 to 1967, the administration of the Northwest Territories was the responsibility of several different federal departments. From 1922 to 1953, various versions of the Northwest Territories and Yukon Branch were administered by the Department of the Interior (1922-1936) and the Department of Mines and Resources (1937-1953). During these years, this administration was run almost exclusively from Ottawa. In 1953, the branch concerned with the administration of the Northwest Territories, known at that time as the Northern Administration and Lands Branch, transferred to the Department of Northern Affairs and National Resources. The Northern Administration and Lands Branch expanded rapidly in the 1950s and in 1959 it was renamed the Northern Administration Branch. This coincided with a reorganization of the responsibilities handled by the Branch. The responsibility for northern affairs was divided into six divisions: 1) Territorial Division; 2) Education Division; 3) Industrial Division; 4) Welfare Division; 5) Resources Division and 6) Engineering Division. In conjunction with this reorganization, a program of decentralization of the field operations of the Northern Administration Branch was enhanced by the creation of two new regional offices. The Administrator of the Mackenzie was stationed in Fort Smith, while the Administrator of the Arctic, stationed in Ottawa, was responsible for the Districts of Keewatin and Franklin, as well as Inuit affairs in arctic Quebec. In 1966, the Department of Indian Affairs and Northern Development supplanted the Department of Northern Affairs and Natural Resources. In 1967, Yellowknife was established as the capital of the Northwest Territories and the transfer of responsibilities from the Northern Administration Branch to the Government of the Northwest Territories began. The transfer rendered the Northern Administration Branch obsolete and during 1968, the Territorial Relations Branch replaced it.

The Department of Social Services was established in 1978 when the Department of Health and Social Services was split to form two distinct departments.

The Department of Social Services was responsible for promoting, improving and preserving the social well being of the residents of the Northwest Territories. The department provided services directly to individuals and families and supported the delivery of services through community-based organizations and agencies. Community Social Services Workers were placed in most communities and provided financial assistance assessments, investigated complaints of child neglect and abuse, supervised probationers and parolees and provided counseling to children and adults. The department assisted groups in organizing and providing services to the aged and handicapped, operated child care facilities, adult and youth correctional centres and homes for handicapped and elderly persons requiring assistance. In addition, funding was provided for foster homes and home support services to enable residents to remain in their homes as long as possible. Awareness programs and training were offered in the prevention of drug and alcohol abuse, domestic abuse and child abuse.

The Administration Activity was responsible for developing, coordinating and managing the delivery of services related to child welfare, special services, financial assistance services, alcohol and drug programs, institutional and community corrections services and programs for the elderly and disabled in Yellowknife and within the communities. This Activity provided the funds for all staff within these programs, except those working in institutional settings. As the Department of Social Services evolved, this activity became responsible for development of policies and management of the department to ensure consistent application of policy, programs, standards and procedures throughout the Northwest Territories. In 1988, this activity was renamed the Directorate; it consisted of the Deputy Minister's Office, the Policy and Planning and Finance and Administration Support Divisions, the Regional Superintendents and their support staff, and Community Social Service Workers located in the communities throughout the Northwest Territories. The Directorate was also responsible for the delivery of the Youth Initiatives Program that assisted community groups that were interested in developing youth leadership programs, drug and alcohol prevention programs and educational and counseling programs.

The Corrections Activity was comprised of institutional corrections programs and community-based corrections programs. The institutional corrections programs provided custody, supervision and rehabilitative treatment to persons sentenced to jail terms in the Northwest Territories. Wilderness programs, education and life skills training were offered within the correctional facility that provided inmates with skills appropriate to the north that would encourage self-reliance and responsibility. The institutional corrections programs also provided probation, parole services and offered programs to help offenders adjust to community life after their release. The community-based corrections programs provided an alternative to incarceration for the offender and offered greater public protection through crime deterrence and offender rehabilitation. The Fine Options program for example, enabled persons who could not pay fines to do community service as a substitute. The Victim/Offender conciliation program was another program administered by community agencies through service contracts. Staff training and a Correctional Officer training program, geared towards aboriginal northerners, was also offered through this activity. Community service, restitution and work programs were other major programs delivered by this division. The Corrections Division was involved with the upgrading of correctional facilities, as well as the construction and opening of facilities within the communities, such as the South Mackenzie Correctional Centre and Baffin Correctional Centre. Corrections Services were also responsible for developing crime prevention programs in the communities of the Northwest Territories. In 1988-89, the Correction Services Activity expanded to include a Custody and Community Corrections program for Young Offenders. Emphasis was placed on improving educational and life skills programming within the already established young offender facilities, as well as constructing two permanent facilities in Iqaluit and Yellowknife. The division continued to emphasize alternatives to institutional care for young offenders through measures administered by Youth Justice Committees that utilized community resources such as probation services and community service orders. In 1993-94, the Department of Justice assumed the responsibility for Corrections Services.

The Family and Children's Services Activity was responsible for providing services relating to Child Welfare, Child Day Care, Child Sexual Abuse and Family Violence Prevention. The activity provided substitute care for children in the custody of Child Welfare, under the Child Welfare Ordinance or Juvenile Delinquent Act. Substitute care resources included adoptive homes, foster homes and group homes. Receiving home facilities such as Trailcross and River Ridge (Fort Smith) provided assessment and treatment services for adolescents; Northern Lights (Inuvik) and the Yellowknife Receiving Home provided group home treatment and family crisis services. The Family and Children's Services Activity emphasized community involvement in responding to child welfare needs and workshops and programs were offered in order facilitate that involvement. In 1981, the Hay River and Fort Providence Dene bands, with assistance from the Department of Social Services, successfully organized and operated three summer camps for young people in order to prevent young people to from coming into conflict with the law. The camps were then used as bases for fall and winter trapping activities in which juvenile offenders would be under the supervision of experienced trappers and hunters. The activity evaluated programs and facilities and offered training programs to staff in dealing with behavioral and emotional problems of children and families. This activity developed a childcare diploma program that was delivered by Arctic College in 1987. Family and Children Services also became involved with custom, private, departmental and international adoptions in the late 1980's. When the Child Day Care Facilities Act and Regulations came into effect in 1988, this activity assisted child day care facilities in becoming licensed and then was responsible for inspecting and monitoring day care centres throughout the Northwest Territories. The day care program also administered grants and contributions to licensed day care operators and offered training assistance to day care staff. In 1986-87, a Spousal Assault Service was introduced to the Department of Social Services and joined the Family and Children's Services Activity in 1988. The primary function of this activity was to develop family violence programs that would encourage and enable families and communities to help themselves and to provide safety and assistance for those living with violence. Community crisis centres were developed, as well as, shelter programs and counseling services for assault victims and for the batterers.

In 1980, the Services to the Aged and Handicapped Activity was added to the Department of Social Services. This activity provided funds and guidance to purchase and provide services to assist the elderly and disabled people to maintain themselves in their own home or community. Coordinated home care programs such as protective visiting, the delivery of meals and home nursing services were delivered through cooperation from hospitals. Studies and need assessments were conducted to determine the needs of handicapped people and elderly people in the north. This activity was responsible for a wide range of personal, community and residential services for the aged and handicapped. This involved the development of appropriate standards and policies, as well as planning services and constructing facilities.

Financial Assistance Services, formerly known as Income Maintenance (1978-79), provided social assistance, supplementary benefits to recipients of Old Age Security plus the Guaranteed Income Supplement and provided financial assistance for payment of non-insured health services for persons who were unable to pay the cost. This activity also identified the various types of interventions and counseling that were offered by the department in order to develop self-support and problem solving to those in need. Community Social Service workers provided counseling in order to teach life skills and promote self-support. In 1988-89, this activity joined with the Aged and Handicapped Services to form Community and Family Support Services.

The Community and Family Support Services Division provided services and financial assistance to the aged and handicapped persons and to individuals and families in financial need. This division also facilitated and monitored the transfer of social services programs and services to local governments under the Government of the Northwest Territories Transfer Policy. The Financial Assistance service within this division provided financial support to persons requiring assistance in meeting their basic needs, day care subsidies to parents and supplementary benefits to qualified northern recipients of Old Age Security and the Guaranteed Income Supplement and the Senior Citizen Supplementary Benefit Act. The division also provided information and assisted community and band councils interested in assuming increased responsibility for program delivery. The division processed and approved applications for rehabilitation programs and provided for an appeal process. Through an employment enhancement program that was cost shared with the federal government, recipients of social assistance were placed in job training programs for guiding, outfitting, tool making, carving, skin preparation, sewing and academic upgrading.

In 1981-82, the Alcohol and Drug Service was added to the Department of Social Services. This activity provided contribution funding to support community-based alcohol and drug projects in order to combat alcohol and drug abuse in the Northwest Territories. The division assisted in the development and delivery of staff training programs for local people that would enable them to work in projects within their home communities. The Alcohol and Drug Service provided administrative services to the Alcohol and Drug Coordinating Council, which included assessment of funding applications and project evaluations. The Alcohol and Drug Coordinating Council employed staff who offered education, counseling and rehabilitation services to community residents. The Alcohol and Drug Coordinating Council also acted as the Regional Advisory Board for the federal National Native Alcohol and Drug Abuse Program. Other major program areas included community education and in-school programs that were designed to increase public awareness of impaired driving and fetal alcohol syndrome. Alcohol Awareness Week was coordinated in conjunction with the Departments of Education and Health and a youth alcohol and drug prevention program was delivered by this activity. Consultative and counseling services were also provided to governmental employees through liaison with the Department of Personnel.

In 1988-89, the activity was renamed the Alcohol, Drug and Community Mental Health Activity. The activity was responsible for facilitating the transfer of community based mental health services and the National Native Alcohol and Drug Abuse Program from the federal government. Emphasis continued to be the development of programs that prevented alcohol, drug and mental health programs at the community level. The Community Mental Health Programs consisted of regional specialists who provided advice, guidance and support to community groups who wished to take an active role in the prevention and treatment of mental health programs. These specialists also provided counseling and crisis intervention services. The Clinical Assessment and Treatment Services provided a team of children's mental health specialists who were available to travel to communities upon request of regional centres. The specialist provided assessments, diagnosis, consultation and treatment for children and adolescents with emotional, behavioural and psychological problems. Between 1990-1991, a Suicide Prevention Program was added to this activity. Work on developing a northern suicide prevention-training curriculum began in Baker Lake, Coppermine, Iqaluit, Fort Smith, Inuvik, Fort Simpson and Yellowknife, which assisted community groups in educating the public about suicide prevention. This activity also provided psychological services to correctional centres.

In 1995, the Department of Social Services and the Department of Health were consolidated to form a single department called the Department of Health and Social Services.

Yellowknife Health and Social Services Authority (YHSSA) was created in 1997, partially from the disbandment of the Mackenzie Regional Health Services. The scope of the authority has expanded since its creation and includes responsibility for the delivery of services to Dettah, Fort Resolution, Lutsel K'e, Ndilo and Yellowknife. YHSSA is responsible for the deilvery of a full range of health and social services programs. It works cooperatively with the other regional health authorities across the Northwest Territories. It maintains a close working relationship with Stanton Territorial Health Authority and the Dept. of Health and Social Services.

The operations of the YHSSA are overseen by a Board of Directors. Members of the Board are appointed by the Minister of Health and Social Services. The day-to-day operations are managed by a Chief Executive Officer.

In August 2016 health and social services authorities across the territory were unified under the Northwest Territories Health and Social Services Authority (NTHSS), and the YHSSA was renamed the Northwest Territories Health and Social Services Authority, Yellowknife Region (NTHSSA-YK).

The Dehcho Health and Social Services Board (DHSSB) was incorporated in May 1997 as part of the Government of the Northwest Territories' (GNWT) initiative to transfer responsibility for the administation of services to the communities. Prior to 1997, the administation of health and social service programs to communities in the Dehcho was managed by Mackenzie Regional Health and Social Services. Through a Memorandum of Agreement, the GNWT delegated responsibility for the administration of health and social services to the DHSSB. The new Board became accountable for setting the direction for health and social services to nine communities in the Dehcho region: Fort Liard, Fort Providence, Fort Simpson, Hay River Reserve, Jean Marie River, Kakisa, Nahanni Butte, Trout Lake, and Wrigley. The Authority administers all public health, home care and general physician services throughout the region, as well as all regional health and social services program delivery to approximately 3,300 residents.

In June 2002, The Board officially changed its name to the Dehcho Health and Social Services Authority (DHSSA). The regional office of the DHSSA is located in Fort Simpson and is governed by a Board of Management comprised of nine Trustees representing the nine Dehcho communities under its jurisdication. The formal mandate of the DHSSA is to "plan, manage, and deliver a full spectrum of community and facility-based services for health care and social services." The regional office is responsible for the overall administration and management of health and social services program delivery. Delivery of health and social services programs in the communities are most commonly delivered at community health centres or other health-related facility.

In August 2016 health and social services were unified under the Northwest Territories Health and Social Services Authority (NTHSS), and the DHSSA was renamed the Northwest Territories Health and Social Services Authority, Dehcho Region.

The Department of Social Development was created in 1967 when the Government of the Northwest Territories was centralized in Yellowknife. The mandate of the Department was to provide social and health care services to Territorial residents. Originally, the Department had three divisions: Alcohol Education Program, Corrections Service and Probation Service. In 1969 the Probation Service was included in the scope of Corrections Services Division. Child Welfare, Medical Social Services and Rehabilitation, Social Assistance and Categorical Allowances were also added to the Department. Medical Social Services and Rehabilitation focused on the problems associated with illness and hospitalization as well as the special needs of aged, disabled and infirm. Correctional Services oversaw probation services, correctional institutions such as the Yellowknife Correctional Institution and the Baffin Correctional Centre in Frobisher Bay, the Correctional Camp until its closure in 1973, and the Juvenile Training Centre in Forth Smith. The Alcohol Education Program focused on individual counseling, referral and education, as well as broad-base community work on finding long-range answers to drug abuse problems. In 1970, Categorical Allowances was renamed Blindness and Disability Allowances. Child Welfare was created in 1970 due to the Jubinville Committee’s major recommendations; one of which was to integrate juvenile delinquency services with child welfare. In 1971, Health Insurance Services was transferred from the Territorial Secretary. HIS was responsible for carrying out the requirements of the Territorial Hospital Insurance Ordinance and the Medical Care Ordinance, both implemented in 1971. This enabled budgetary and funding changes for Territorial hospitals. Additionally, the Health Care Plan was created to provide health services for all Territorial residents. In 1972 Medical Social Services became Medical Social Services and Special Care. In 1973 the Department created the Community Social Services division. In 1974 the Alcohol and Drug Program was responsible for the Alcohol and Drug Co-ordinating Council, but did not list it as a responsibility past that year. In 1975 the blanket Special Services Division was created to manage the development, maintenance and coordination of community based social services in its divisions of Child Welfare, Juvenile Probation, Day Care, Homemaker Services, and Aged and Handicapped Services. By 1976 it only listed its divisions as being Child Welfare and Aged and Handicapped Services. In September 1977 the Department was renamed Health and Social Services.

The Department of Education, Culture and Employment was established in August 1992 with the amalgamation of the Department of Education with the Department of Culture and Communications.

The Department of Education, Culture and Employment has been responsible for the following: providing school programs and services; museums and heritage programs; public library services, television and radio programs and services; culture and language programs and services; public and private sector training, income support programming, post-secondary education and college programs and services. The department's objective is to enable the people of the Northwest Territories to reach their full potential and to contribute to the cultural, social and economic development of the Northwest Territories.

The Directorate and Administration Activity provides for the overall management and administrative support under the direction of the Deputy Minister who recommends the goals, objectives and standards of the department to the Minister. This includes strategic planning, development of legislation and policy, budget co-ordination, capital planning, financial services and systems support. It is also responsible for leading government-wide reform and transfer of income support programs to interested communities and enhancing the creation of sustainable jobs through a number of programs and services, such as the labour force plan.

The Advanced Education Activity operated between 1993-1994; it combined all major government-training functions within the department. This involved the administration of the Public Service Career Training Program, Employment and Post Secondary Student Financial Assistance Programs, as well as the monitoring and setting standards for continuing education. The Student Services Division, which was part of this activity, began decentralizing its counseling services to Career Centres within various regions in 1993-1994. The Advanced Education Activity coordinated literacy projects and delivered the following adult training programs: the Northwest Territories Apprenticeship Training Program, Construction Worker Training Program, Training On-the-Job Program and Short Term Employment Program. Education and employment training for social assistance clients, training for present and future government employees, college diploma and certificate programs, short-term skill training courses and university transfer programs were delivered by this activity. College programs administered by Arctic College were also funded under this activity. Arctic College delivered education programs geared specifically to the needs of the northern workforce and economy. In 1994-1995, the College completed its decentralization by establishing head offices in Iqaluit and Fort Smith. This resulted in one college serving the Nunavut area and one serving the western portions of the Northwest Territories. The College operated with funds received from the Department of Education, Culture and Employment. The College also generated its own funding from tuition fees, room and board charges, investment income and contracts with organizations for the delivery of training.

The Culture Activity delivered programs with a cultural emphasis such as the Museums/Heritage program, Public Library Services, Television and Radio Services and the Language Bureau. The Museums/Heritage program was responsible for collecting, preserving, researching, documenting and presenting the cultural and natural history of the Northwest Territories. This function was achieved through museum and archival programs at the Prince of Wales Northern Heritage Centre and the Northwest Territories Archives, as well as through the provision of advice, technical support and financial contributions supporting community heritage projects. Other territorial programs administered by the activity included archaeological resource management and the geographic names research program. Library Services provided some financial assistance to community libraries through grants and contributions programs. The service provided funding to municipal councils for the operation of library programs, as well as the training of local staff through regional and distance education courses. The Language Bureau provided interpretation, translation and other communications services to the Government of the Northwest Territories and the Legislative Assembly in all official languages of the Northwest Territories, except Cree. The Language Bureau included both an aboriginal language and French language section. Aboriginal languages broadcasting and community services were the major focus of Television and Radio Services. This service was involved in the production and broadcasting of programs through Television Northern Canada (TVNC) and provided contributions to community broadcasting societies and regional native communications societies to support the production and broadcast of culturally relevant radio and television programs in aboriginal languages. Television and Radio Services was also responsible for the maintenance of television and radio facilities in 27 small communities throughout the Northwest Territories. The Culture Activity combined with the Advanced Education Activity in 1995-96 to become the Culture and Careers Division. However, Library Services and Television and Radio Services became the responsibility of the Educational Development Division and formed the basis for Information Networks.

In 1994-1995, the Culture and Careers Branch was created by combining programs and services related to Culture and Heritage, Museums, Language Bureau, Colleges and Continuing Education, Career Development and Student Financial Assistance, Employment Support programs, Human Resources Development for Government of the Northwest Territories employees and Child Day Care. This branch intended to increase flexibility for their programs and services in order to allow communities and regions to have a greater role in determining their own priorities. The division was responsible for a long-term plan for human resource development, which included mining industry training programs, career counseling for community staff and youth employment initiatives. In 1999-2000, this division was renamed Advanced Education and Careers Division when the programs and services related to culture, arts, heritage, museums and language were moved to the Educational Development Division which was then renamed the Education and Culture Division. The Advanced Education and Careers branch provided a range of programs and services related to career development, employment development and support programs, the College, continuing education and income support. The branch continued to coordinate human resource development activities across the Government of the Northwest Territories.

The Educational Development Branch, formerly the Schools Activity, oversaw the delivery of K-12 schooling, inclusive schooling and residence programs; development and implementation of K-9 curricula; the implementation of secondary curricula adapted from Alberta and the monitoring and evaluation of school jurisdictions. This division was also responsible for the delivery of professional training programs; support for the development and delivery of early childhood programs; and the development of public information and distance learning systems, including public libraries; television, radio and internet services. The Educational Development Branch placed an emphasis on the community development of programs, improved access and the use of aboriginal languages and student support. Between 1995-1996, Library Services and Television and Radio Services were moved from the Culture Activity to the Education Development Branch to form the basis for Information Networks. The focus of Information Networks was to cooperate with other Government of the Northwest Territories departments and private sector organizations in order to improve telecommunications links to communities. The department provided information and system training, as well as providing for the establishment of interconnecting networks for all educational institutions and municipal networks in all communities with more than one educational institution. This division was renamed the Education and Culture Branch in 1999-2000, when the cultural, arts, heritage, museums and language programs were transferred from the Culture and Careers Division.

In 2005-2006, there were three major changes that impacted Education, Culture and Employment. The first change was establishment of an Official Languages Division based on recommendations made in a report by the Special Committee on Official Languages to the Legislative Assembly. The recommendations were accepted by the Legislative Assembly and served as the basis for a number of adjustment to the Official Languages Act; establishment of the Official Languages Board and the Aboriginal Language Revitalization Board; publication of an annual Official Languages Report and the issuance of the Aboriginal Culture and Language Directive for school authorities. The report also called for the establishment of an organizational structure to lead the GNWT involvement in language matters. As a result, effective April 1 2005 a Languages Division was established that reported to the Deputy Minister. This Division will serve a leadership role in language policy and regulatory matters. As well, Division staff will direct the coordination of language activities across the GNWT. In 2005, the GNWT also decided to consolidate labour services functions with employment activities. As of April 1, 2005 the Labour Services Unit and responsibility of the Labour Standards Board, were transferred from the Department of Justice to Education, Culture and Employment. The third change that came into effect on April 1, 2005 was the transfer of public housing and rent subsidies from the NWT Housing Corporation to the Department. This action was linked to the broader initiative of the GNWT and legislators to establish a general policy framework for all income security programs and to consolidate programs where possible.